Dr. Giuseppe D’Orazio | Nanobiotechnology | Best Researcher Award
University Researcher at University of Milan | Italy
Dr. Giuseppe D’Orazio is an accomplished academic researcher currently serving at the University of Milan, where he focuses on Organic and Carbohydrate Chemistry with applications in drug discovery, materials science, and biomedical research. His professional journey reflects a strong interdisciplinary approach, bridging chemistry and biology to address pressing challenges in pharmaceuticals, crop protection, and biomaterials. With more than fifteen years of post-graduate experience, he has contributed to both academia and industry, building an impressive portfolio of publications, patents, and collaborative projects across Italy and Europe. His research stands out for its innovative exploration of glycoderivatives, carbohydrate-based materials, and nanotechnology-inspired biomedical tools.
Profile
Orcid | Scopus | Google Scholar
Education
Dr. Giuseppe D’Orazio educational path reflects his deep dedication to biotechnology and chemistry. He earned his Bachelor’s degree in Biotechnology from the University of Milano-Bicocca, graduating with top honors for his thesis on the synthesis of iminosugar analogues as glycosidase inhibitors. He then pursued a Master’s degree in Industrial Biotechnology, specializing in Organic Chemistry, with research on sodium-glucose co-transporter (SGLT1) modulators that demonstrated strong anti-inflammatory properties. His academic development culminated in a PhD in Organic and Bioorganic Chemistry from the same university, with a dissertation titled “Glycoderivatives: drug candidates and molecular tools.” As part of his training, he gained international experience as a visiting PhD student at CICbiomaGUNE in Spain, where he worked on functionalizing gold nanoparticles with bioactive compounds.
Experience
Dr. Giuseppe D’Orazio professional career encompasses both academic and industrial research environments. He began with research fellowships in analytical chemistry, focusing on food traceability and nutraceutical analysis. he served as a postdoctoral researcher at the University of Milano-Bicocca, where he investigated bioactive molecules of pharmacological interest, trained students, and contributed to teaching activities. He also gained consultancy experience with Eisai s.r.l., where he carried out chemical analysis of drug stability. he transitioned into industry as a Chemistry Researcher at Isagro S.p.A., leading projects in agrochemical discovery and developing novel crop protection agents, while also filing multiple patents. His academic career resumed at the Polytechnic University of Bari where he focused on functional and sustainable materials before joining the University of Milan as a researcher in Organic Chemistry. In his current role, he develops carbohydrate-based molecules, glycoconjugates, and nanostructures with applications in vaccines, immunology, and cancer therapy.
Research Interests
His research interests span a wide range of disciplines within chemistry and biotechnology. Central to his work is Carbohydrate Chemistry and Glycoconjugates, with applications in biomedical sciences, including the design of vaccine adjuvants and cancer therapeutics. He has a strong interest in synthetic organic chemistry, particularly in the development of new ligands, glycoderivatives, and bioactive molecules. His work also explores gold nanoparticle functionalization, aiming to create nanoscale tools for drug delivery and immune modulation. Additionally, he has contributed to crop protection chemistry, discovering new molecules for plant health and sustainability, and to analytical chemistry, developing techniques for structural characterization and evaluating the biological efficacy of compounds.
Awards
Dr. Giuseppe D’Orazio has received several recognitions for his scientific contributions. Among them, he won the Best Poster Award at the XVIII Conference-School on Carbohydrate Chemistry, for presenting innovative vaccine adjuvant research inspired by the lipid A structure of Bacteroides fragilis. He has also been entrusted with significant editorial roles, serving as a guest editor for special issues in journals such as Applied Sciences and Biomedicines. His expertise is recognized through appointments to advisory panels, journal reviewer duties, and participation in international collaborative research projects funded by European and Italian institutions.
Publications Top Notes
Dr. Giuseppe D’Orazio has authored more than 30 peer-reviewed papers and one book chapter, with a citation record exceeding 700 citations on Google Scholar. Below are seven representative publications:
Title: Gold Nanoparticles functionalized with ABO Blood Sugar Antigen as Nanotools for Biomedical Applications. Carbohydrate Research.
Year: 2025
Citations- 3
Title: Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles. Advanced Science.
Year: 2024
Citations: 15
Title: Anti-Inflammatory Effects of SGLT1 Synthetic Ligand in In Vitro and In Vivo Models of Lung Diseases. Immuno.
Year: 2024
Citations: 10
Title: Synthesis of a Small Library of Glycoderivative Ligands of SGLT1. Molecules.
Year: 2024
Citations: 08
Title: Domino Reactions on Carbohydrates: State of the Art. European Journal of Organic Chemistry.
Year: 2024
Citations: 12
Ttile: Semisynthetic Glycoconjugates as Potential Vaccine Candidates Against Haemophilus influenzae Type a. Chemistry – A European Journal.
Year: 2024
Citations: 09
Title: Dual-Targeting Gold Nanoparticles: Simultaneous Decoration with Ligands for Co-Transporters SGLT-1 and B0AT1. Applied Sciences.
Year: 2024
Citations- 07
Conclusion
Dr. Giuseppe D’Orazio career demonstrates a consistent pursuit of innovation at the interface of chemistry and biology. His work in carbohydrate chemistry, nanomaterials, and bioorganic synthesis has produced both fundamental insights and practical applications in medicine and agriculture. With a strong background in industrial research and academic scholarship, he exemplifies the modern interdisciplinary scientist who bridges discovery with application. His contributions, spanning publications, patents, and international collaborations, underline his role as a forward-looking researcher whose efforts are shaping advancements in biotechnology, organic chemistry, and drug discovery.